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[DOI] [PMC free article] [PubMed] [Google Scholar] Lin H., Yang C., Yin M., Qiu J., Wang W., Lu J., Xu D., Li G., Deng C
Among the mechanisms leading to global DNA de-methylation/hypomethylation, an important one is the oxidation of 5 mC to 5-hydroxymethylcytosine (5 hmC), which serves as an intermediate in active DNA demethylation [118,119]
However, the mechanisms by which AEC2 cell dysfunction contributes to these diseases remain a challenging question (Figure 1)
R Foundation for Statistical Computing, Vienna, Austria
