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found that ARID1A mutations confer sensitivity to pan-HDAC inhibitors such as SAHA in OC, which is associated with more significant effects of growth inhibition owing to suppression of HDAC2 activity (189)

High cortisol levels can interfere with muscle building and fat loss by promoting catabolism (the breakdown of muscle tissue)

Deciphering depression: epigenetic mechanisms and treatment strategies

doi: 10.1093/humupd/dmac035 3 YounglaiEVHollowayACFosterWG
