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4KO cells exhibited slower growth without DNA damage and a greater sensitivity to IR (Supplementary Fig
Indeed, treatment of mice bearing autochthonous breast cancers, or cancer allografts, with CDK4/6-inhibitors together with anti-PD-1/PD-L1-antibodies enhanced the efficacy of immune-checkpoint blockade and led to complete tumor regression in high proportion of animals (114, 115, 118)
The peptide helps endothelial cells form capillary-like structures, essential for angiogenesis
