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57,58 Accumulated DNA damage and cellular senescence are thought to be a common underlying mechanism linking infertility, cancer, cardiovascular disease, and other chronic diseases

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By selectively inhibiting NNMT , 5-Amino-1MQ can reduce the methylation of nicotinamide, leading to increased intracellular NAD availability and enhanced metabolic activity

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Sun C, Rosendahl AH, Wang XD, et al

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