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Another relatively novel role of NAD + is involvement in forming non-canonical caps on the 5 end of RNA that mark RNA for degradation in eukaryotes 337339
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In contrast, cholesterol levels in the NNMT inhibitor-treated DIO mice were similar to cholesterol levels reported by the vendor for age-matched normal chow-fed C57Bl/6 mice (www.jax.org/jax-mice-and-services/find-and-order-jax-mice/most-popular-jax-mice-strains/dio-b6)
