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NOX, activated by the inflammation process, enhances oxidative stress 32,33

PEG forms a hydrophilic steric shield that minimizes opsonization and phagocytic uptake, significantly extending the circulation half-life of the encapsulated therapeutics [97, 98]

Li, Z., Jiang, Z., Fei, B., Liu, X., and Yu, Y

EA has been proven to exert anti-proliferative effects on tumor cells and increases the cytotoxicity of several alkylating agents such as melphalan, carmustine, mitomycin C, and nitrogen mustard
