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Robinson et al., In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift

ROS are formed as by-products, during normal aerobic metabolism, and could damage all biomolecules and cause cell death.14 However, in order to maintain the redox homeostasis in the cell, a variety of enzymatic (catalases, SODs, and peroxidases) and non-enzymatic (glutathione) defense mechanisms are induced
A defined design space should replace empirical trial-and-error, enabling controlled batch-to-batch consistency

[DOI] [PubMed] [Google Scholar] 74.Sudhahar V., Shaw S., Imig J
