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Description
Anti-neuronal antibodies interact with neuronal surface antigens and activate microglia, leading to the damage of dopaminergic neurons, ultimately resulting in TS

MMPs-2, -7, -9, -12 and -13 favour pro-inflammatory signalling pathways and increased barrier permeability

AMPT exerts its inhibitory actions on tyrosine hydroxylase, which will lead to a severe impairment in the endogenous production of dopamine [25, 31]

doi: 10.1002/jcp.27296 100 DaiWLeeD
