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Pluronic micelle-encapsulated Disulfiram targets cancer stem-like cells and reverses pan-resistance in acquired resistant breast cancer cell lines

In addition, polymeric poly(styrene-comaleic anhydride) (PSMA)-NPs and conjugated polymer poly[2-methoxy-5-(2-ethylhexoxy)-1,4-styreneyl](PPV) -PSMA-NPs nanoparticles prepared by nanoprecipitation have also been shown to reverse the immunosuppressive TME by reprogramming TAMs, and which can not only specifically target TAMs but also directly inhibit tumor growth by repolarizing TAMs to kill tumor M1 phenotype (60)

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Comparing platelet levels before and 30d after treatment showed FOXO4-DRI not to noticeably influence platelet levels (Fig
