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Six new ligands of the Tri-Click (TC) class were prepared and their ability to coordinate three copper(II) ions was determined using electrospray ionisation-mass spectrometry (ESI-MS)

We observed a consistent increase in sensitivity, or reduced IC 50 value, for mutant cells treated with doxycycline but not parental OVCAR5 cells, indicating that induction of mutant p53 sensitized cells to APR-246 (Fig

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Additionally, BPC-157 supports digestive health by protecting the lining of the gastrointestinal tract and promoting gut healing, with few known side effects