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MR uses genetic variation as an independent instrumental variable [27] to estimate the effect of exposure on outcomes, thereby minimizing biases and enhancing the reliability of causal inferences regarding exposure-outcome relationships [28]

doi: 10.1016/j.molmet.2019.06.026 47

Furthermore, to accomplish an inclusive examination strategy for the relevant information, the history of each publication and the indexing of their respective journals were checked for impactful information
