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Description
Furthermore, NRF2 enhances drug resistance by inducing the expression of ATP-binding cassette (ABC) transporters such as ABC sub-family C member 1 (ABCC1) and ABC sub-family G member 2 (ABCG2), which efflux chemotherapeutic agents out of cells
This well-established therapeutic use provides strong evidence for NAC's ability to support hepatic glutathione levels
Additionally, heterogeneities in patient reactions and hazards from oxidizing agents were observed
So, we dont have a lot of natural alpha lipoic acid available to make glutathione
