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A loading phase of 4 to 6 weeks at the higher end of the range is common, followed by a maintenance dose of 1 mg/day three to five times per week

Thus, we determined ER-stress response genes Xbp1 and the ER chaperone heat shock 70 kDa protein 5 (HSPA5, previously known as immunoglobulin heavy chain binding protein [BIP]), inflammation-responsive genes IL6 and IL1, and hypoxia-responsive genes hypoxia-inducible transcription factor 1 (HIF1) and GAPDH

FIGURE 4 DHA + TPPU Decreases the Expression of APP and Activity of AChE The gene expression experimental data showed an increase in the expression of the APP gene, which is encoded for amyloid beta synthesis