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In addition to the role mentioned above in the process of oxidative stress, the GPX family also plays a unique role in tumor development (Laribi et al., 2021), viral infection (Strycharz-Dudziak et al., 2020), obesity (Rusetskaya et al., 2019), signal transduction, and inflammation (Rusetskaya et al., 2019)
doi: 10.1073/pnas.1607571113 [DOI] [PMC free article] [PubMed] [Google Scholar] 408

This metabolic preference bears some resemblance to the Warburg effect observed in malignant tumors [105]
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