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The structure showed the FERM domain has a canonical three-lobe structure (F1F3), and the SH2 has a preserved SH2-like structure despite lacking the highly conserved arginine residue in the phosphotyrosine binding site (71, 72)

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Persistent pain, swelling, reduced range of motion, warmth, or redness can indicate post-injection inflammation, infection, or an improper injection technique that requires medical evaluation

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