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Below, we summarize and discuss the latest advances in three major categories of potential therapeutic strategies, including specific inhibitors of inflammatory pathways, stem cell-based immunomodulatory therapy, and epigenetic regulation interventions, with a focus on their mechanisms of action, preclinical efficacy, and translational potential in the management of varicocele-related disorders

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Therefore, carnitine/acylcarnitine not only play roles in muscle energy metabolism but also participate in the whole-body energy balance and fatigue perception by affecting neuromuscular signaling, underscoring the potential importance of carnitine in exercise physiology, exercise recovery and performance improvement