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The results of cultured ECs and animal models of HHcy indicate that Hcy can injury ECs and cause endothelial dysfunction (60, 61)

Garcia-Reitbock P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, et al

Similarly, a previous preclinical study of VE supplementation did not significantly alter plasma levels of the pro-fibrotic cytokine TGF-1 or the adipocytokine leptin compared to the cholesterol-fed control group
