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Encyclopedia of Clinical Neuropsychology

It does so by activating genes that are associated with repair and regeneration while suppressing those linked to inflammation and aging

Even though TGFb1 treatment in aSyn-overexpressing cells did not lead to a significant increase in the intensity of caspase 3/7 signals as compared to untreated aSyn-overexpressing cells (100 7.3%), a significant decrease in caspase 3/7 signals was observed upon the knockdown of ALK5 (65.0 3.4%), SMAD2 (57.8 6.8%), or DYNLRB1 (77.3 1.3%), indicating a significant decrease in the number of apoptotic cells
