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Catabolic states Clinical investigators have shown that IGF-I levels are often significantly altered in catabolic states, including the acute postoperative period[367], burn patients[368] and chronic catabolic illnesses, such as cystic fibrosis[369] and HIV with wasting[370]

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We used 180 cases RNA-seq of pancreatic ductal adenocarcinoma (PAAD and 4 cases of normal tissue), with clinical information for WGCNA analysis in TCGA ( Meanwhile, we also organized 36 normal samples and 36 tumor samples (GSE15471) of microarray from the GEO database

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