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Another animal study showed that inhibition of TMAO formation can upregulate the host hepatic bile acid synthetic enzyme CYP7A1 and alter the expression of hepatic genes critical for bile acid feedback regulation, thus preventing diet-driven hepatic cholesterol accumulation (Pathak et al., 2020)

and Wall G

Integrative strategies that combine genetic and nutritional approaches to modulate the differentiation pathways of paraxial MSCs toward myogenic or adipogenic lineages and the interaction between muscle and adipose tissues are proposed

doi: 10.3390/ijms18040885, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 169.Frantz NZ, Yamka RM, Friesen KG