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In parallel, MNPs disrupt gut microbial composition, promoting dysbiosis and exacerbating barrier dysfunction
coli with the first plasmid expressing OxyR in pRSF and the second plasmid expressing TrxCp and a fluorescent protein in pET-19b will be included as a control to demonstrate the function of the glutathione enzymes introduced
Decreased DNA methylation of SDHB elevates SDHB mRNA expression in the chorionic villi, which reduces overall succinate accumulation and risk of recurrent spontaneous abortion (59)
