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Oncogene 38 (11), 19791988

Despite the increasing incidence and improving diagnosis of diseases (such as depression, Alzheimers, and autism), there has been significant pruning of CNS drug development ventures by the pharmaceutical industry due to the high failure rates of candidates in clinical trials (approaching 100%) [1,2,3]

As we age, NAD+ levels tend to decline, which is why it has become a focus of longevity research

however, the increases in eradication rates differ among studies (McFarland et al
