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Adenocorticotroph hormone (ACTH)-secreting tumors cause Cushings disease (hypercortisolism), and TSH-secreting tumors present with signs and symptoms of hyperthyroidism
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These mechanisms enhance FoxO-driven expression of both classical and noncanonical E3 ligases, robustly activating UPS (Chen K
[DOI] [PubMed] [Google Scholar] 162.Raizel R., Leite J.S., Hypolito T.M., Coqueiro A.Y., Newsholme P., Cruzat V.F., Tirapegui J
