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Mitophagy in macrophages, as a selective autophagy mechanism, may also influence macrophage differentiation through its impact on ROS levels
No published human clinical trials have specifically evaluated AOD-9604 for osteoarthritis or joint health conditions
doi:10.1136/practneurol-2014-001071
Notably, all patients had previously been treated with pentosan polysulfate, which is currently the only FDA approved treatment for interstitial cystitis, and had not responded
