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If NNMT inhibition both restores adipocyte energy expenditure (promoting fat reduction) and supports myogenic differentiation (preserving or enhancing muscle), the net body composition effect could be recomposition simultaneous fat loss and lean mass preservation

This suggests multiple overlapping fat-loss pathways, making it a resilient addition to any protocol

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[7] Vitamin D toxicity presents chiefly as sustained hypercalcaemia with nausea, vomiting, muscle weakness, neurocognitive changes, or arrhythmias, progressing to nephrocalcinosis if untreated