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Consume Antioxidants: Vitamin C and E-rich foods help regenerate glutathione by reducing oxidative stress

Ferroptosis is an iron-dependent lipid peroxidation and ROS-induced programmed cell death (PCD) modality that relies on iron-mediated oxidative damage, increased iron accumulation, and free radical production, and a fatty acid supply with increased lipid peroxidation is critical for the induction of ferroptosis 22

however, subsequent studies did not confirm this finding and other studies found that the Leu variant was protective rather than disease-associated (see Table 1 and discussion below for details)

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