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Avoiding exercise right before or after taking it can help as well since this will give it time to absorb before you do those movements

[DOI] [PubMed] [Google Scholar] 189.Liu Q, Limthongkul W, Sidhu G, Zhang J, Vaccaro A, Shenck R, et al

NIH research review Found that KPV acts locally in the colon, minimizing systemic side effects seen in traditional IBD medications

These uses are off label