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Elucidating the regulatory mechanisms of Nrf2 sensitivity to ferroptosis in lung cancer cells under cysteine or glucose limitation may lead to novel therapeutic strategies in the clinical management of NSCLC

found that circ_0001273, as a cancer-promoting factor that upregulates SLC1A5 expression by binding to miR-622, which increases Gln uptake by tumor cells, consequently enhancing tumor growth and inhibiting cell apoptosis (57)

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