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As usual, they found that coffee consumption showed no significant association with the bone mineral density of either the femoral neck or lumbar spine

If IGF-1 LR3 levels remain higher than normal for an extended period of time, issues with cardiac rhythm and heart valves may arise

Effective systemic dose in pigs of 1.1 mg/kg (~75 mg in humans) showed no adverse effects, representing approximately 300-fold below toxic dose
