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Description
Gille D, Schmid A
Vet Intern Med 16, 726-731
TB-500 (a Thymosin Beta-4 fragment) acts as a G-actin sequestering peptide affecting cytoskeletal remodelling and cell migration, with effects measured at the actin polymerization level rather than at receptor-pathway level
It inhibits the release of pro-inflammatory factors in response to TLR4 stimulation and induces immune tolerance, a non-butyrate-dependent effect (99)
