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453,454 Ferulic acid can improve the survival rate of copper-overloaded cells, significantly increase the expressions of SIRT1, Nrf2, SLC7A11, and GPX4, and downregulate the levels of MDA, 4-HNE and ROS

Also, the membrane of some cells looked disrupted in a higher or lower grade (Figure 2(b)(4))

One significant factor is the consumption of alcohol

Analysis of Myocilin mutations in 1703 Glaucoma patients from five different populations
