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The resulting cystathionine is converted into cysteine, a precursor of glutathione, and -ketobutyrate by -cystathionase, which is also dependent on pyridoxal-5-phosphate (Fig
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Moreover, research has shown that PCa tissues have increased CXCR3A mRNA levels while CXCR3B mRNA levels are downregulated
503 A significant milestone was the identification of the first small-molecule chemical probe, SGC-iMLLT, which targets ENL and its paralog AF9
