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Blood tests are required to diagnose this condition
For instance, while quercetin has been reported to activate both enzymes, curcumin has shown potential as an activator of SIRT1, promoting its deacetylase activity and contributing to anti-inflammatory effects 178

Mitochondrial Peptides and Metabolic Regulation. Cell Metab

Anticancer Res 30:11691181 Bowen M, Orvig C (2008) 99 m-technetium carbohydrate conjugates as potential agents in molecular imaging
