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There is a growing body of evidence that suggest that dysfunctional microglia, oxidative damage, and mitochondrial dysfunction can play compelling roles in BD etiopathogenesis

In a large analysis , people with type 2 diabetes who took 1 mg of semaglutide lowered their A1c by an average of 1.77% after 26 weeks compared to 1.09% with the highest dose of metformin

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Healthcare providers often need to reduce the doses of these concurrent antidiabetic medications when starting semaglutide therapy, with subsequent adjustments based on glucose monitoring results and clinical response