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Description
Electron microscopic analysis has shown that 48 h after LPS treatment, the glycocalyx of glomerular endothelial cells and podocytes begins to disappear, and endothelial fenestrations are lost or edematous, such that a gap forms between the podocytes and the basement membrane (15)
muciniphila also improves age-associated colon mucus thinness and changes in inflammation and immune mediators

NLRP3 also influences macrophage polarization, ensuring timely transition from pro-inflammatory to pro-repair phenotypes
Journal of Periodontology , 74 (9), 1282-1292
