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Mercaptopropionylglycine showed protective activity against cardiac reperfusion/ischemia injury ( Amifostine is hydrolyzed in vivo to WR-1065, which is also clinically used during radiotherapy as a protectant (WR stands for Walter Reed Army Hospital where this compound, and many other of the WR series, were developed) (Nair et al., 2001)

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Structure-function of the high affinity substrate binding site (S1) of human norepinephrine transporter