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Most people alternate nights or apply copper peptides first and wait before a retinoid, since stacking them raises irritation

[DOI] [PubMed] [Google Scholar] 93.Narayanan S., Bhutiani N., Adamson D.T., Jones C.M
doi: 10.1002/mus.23662

however, 70% of patients develop motor fluctuations after 9 years of CD/LD treatment [5] that are characterized by episodes of suboptimal response to medication, resulting in the reappearance or worsening of their symptoms (OFF episodes) [1]
