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Description
82 WilkinsK
GHK-Cu increased production of nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4), sped up regeneration of nerve fibers from nerve stubs, and increased axon count and proliferation of Schwann cells compared to controls
One of the key molecular sensors driving this adaptation is AMP-activated protein kinase (AMPK)
In some foals affected by this neonatal syndrome, there is minimal ischemic necrosis but instead a profuse distribution of small perivascular and petechial hemorrhages in the cerebrum, cerebellum, and brainstem
