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Experimental studies in Wistar rats treated with PZA or PA showed hepatotoxicity, as demonstrated by elevated serum alanine aminotransferase, aspartate transaminase, and galactose single-point levels (Tostmann et al., 2008

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Spiking of known amount of tissue (hepatic or cardiac) with serial concentration of authentic GSSG prior to extraction and derivatisation produced a linear curve

17 , 316 (2004) Meneses-Lorente, G., Sakatis, M.Z., Schulz-Utermoehl, T., De Nardi, C., Watt, A.P.: A quantitative high-throughput trapping assay as a measurement of potential for bioactivation