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Furthermore, a chronic inflammatory state in the nervous system intensifies with age, leading to increased microglial activation and elevated levels of proinflammatory cytokines, such as tumor necrosis factoralpha (TNF) and interleukin1 beta (IL1), detectable even preclinically [63, 64]

It is also worth noting that other factors affecting gene expression, not within the scope of this review, including histone modifications and RNA methylation, may also be important in the life cycle of OLG lineage cells [83, 105, 115], and it is likely that combined effects from such factors contribute to OLG function both in health and disease

More often than not, it's used as a photostabilizer rather than a proper sunscreen agent as it can protect formulas nicely from UV damage