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Description
Because of lack of renal clearance, serum values rose to more than a hundredfold from 422 pmol/L on average to 54 000 pmol/L, with 67 000 pmol/L as highest value, without side-effects

Kinins and small signaling peptides affect local blood flow and gland secretion
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When electrocardiography was performed, the rats in the study had signs of heart failure and ischemic signs
