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Infected PBMCs were maintained at 37C, with 5% CO 2 until they were terminated at 8 and 15 days post-infection, the time determined for sufficient granuloma formation
Once interferon- binds to its receptor, there is activation and phosphorylation of STAT1, leading to transcription of IFN--stimulated genes [18]
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In addition, P53 can also indirectly mediate ferroptosis through metabolic target genes such as SAT1 [86], FDXR [87] and GLS2 [26]
