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Leventhal, D

A brief halt in the surgical treatment of PD was seen in the 1960s after levodopa was discovered to reduce the symptoms of the condition significantly

Vitamin E, a key fat-soluble antioxidant, has the most evidence for its ability to provide a therapeutic benefit [2]

The progressive loss of nephrons reduces renal 1-hydroxylase activity, limiting the production of active 1,25-dihydroxyvitamin D (1,25(OH)D), whereas urinary loss of vitamin D-binding protein (VDBP) due to proteinuria further exacerbates 25(OH)D deficiency (3)
