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For a more detailed history and the request for comments on the proposed rule, initially published on January 12, 1979, see 44 FR 2932 The 1979 FTC Staff report (PDF) titled Drug Product Selection contains a detailed history of antisubstitution laws, the transition to substitution laws, pricing, and estimated savings from adopting substitution laws

This means they do not compete for the same metabolic pathways, which eliminates one of the most common sources of drug-drug interactions

Its best to take vitamin C at least 2 hours after taking a vitamin B12 supplement

Their Methylcobalamin Injection, Nervon, is made using the best ingredients and quality standards