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Description
[PubMed: 17512232] 226

Although the exact mechanistic details are still subject of discussion, reduction of these bonds (SH) is suggested to be associated with a conformational change and significant inactivation of the enzyme [20,35,43,44]
Two patients, one with colon cancer and one with rectal cancer, experienced transient stable disease of 44 and 54 days

Ageing, neurodegeneration and Parkinson's disease
