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Carnitines role in brain health: Besides fertility, carnitine is implicated in brain plasticity and cognitive functions, with acetylcarnitine influencing gene expression through histone acetylation

Targeted ablation of VDR in cardiomyocytes leads to cellular hypertrophy, cardiac enlargement, and impairments in both systolic and diastolic function ( 6 Modulating gut microbiota dysregulation may improve HFpEF In patients with HFpEF, gut microbiota dysregulation is prevalent and may positively impact pathophysiology by modulating gut microbiota or their metabolites through interventions such as probiotics, fecal microbial transplantation (FMT), prebiotics and replenishing gut microbiota metabolites ( Figure 4 )

These data suggest that LMP formulation increases the bioavailability of creatine when given at 51 mg/kg
