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For instance, inhibiting NNMT in white adipose tissue using small molecule inhibitors (like 5-Amino-1MQ analogs) increased energy expenditure and reduced weight gain in diet-induced obese mice, independent of food intake (Kraus D, 2014)
M.SeibelP.MoschettaA.CoccoT.VillaniG
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As defined by our analysis, we found that the majority of genes in both sets exhibited high levels of promoter-associated H3K4me3 and low levels of enhancer-associated H3K27ac
