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In vitro evaluation of pH-sensitive liposomes loaded with d-limonene in targeting human malignant glioma cells
This is consistent with the phase 2b clinical trial, where the total 12-week result was 2.8kg (6.2 lbs) additional fat loss versus placebo (clinical trial data)
Forde et al., 2019
Some drugs are metabolised before reaching the systemic circulation, this is called the first-pass effect
