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While PEG is non-biodegradable 96 , PLGA is metabolized into non-toxic byproducts (lactic and glycolic acids), making it a biodegradable and a biocompatible polymer 97

The Firmicutes/Bacteroidetes ratio (F/B ratio), a key indicator of microbial community structure, has been associated with multiple pathological conditions, including metabolic disorders [136]

The estimated validation parameters were correct and met the requirements dedicated to biological sample analysis 33
Oxidative stress is considered as an imbalance between pro- and antioxidant species, which results in molecular and cellular damage (Conti et al., 2016)
