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MSCs have emerged as a viable clinical strategy in recent years due to their excellent properties, including easy separation, multipotent differentiation potential, and strong paracrine activity, which provide new opportunities for kidney disease therapy and prognosis

This differentiation plasticity can be attributed to the embryonic history of melanocytes, which are derived from the neural crest, a transient, migratory, and multi-potent population of cells that can differentiate into diverse cell types (Sauka-Spengler and Bronner-Fraser, 2008)

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